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CB Therapeutics Breaks Ground on Sustainable Ergoline Biosynthesis Through Precision Fermentation

Carlsbad, CA – January 9, 2025 – CB Therapeutics, a U.S.-based synthetic biology company

known for its innovative bio-manufacturing solutions, today announced the expansion of its

platform to include ergoline-based compounds. Ergolines—structurally related to alkaloids

naturally found in ergot fungi—hold broad potential in areas ranging from neurological research

and psychiatric applications to treatments for migraines, postpartum hemorrhage, and

Parkinson’s disease. Building on its proven precision fermentation platform, CB Therapeutics

now offers a scalable, eco-conscious pathway for producing these high-value molecules with

unmatched consistency and purity.

 

While many recognize ergolines through their association with lysergic acid

derivatives—including LSD—this diverse class of compounds has long been investigated for

numerous medical and research applications. Traditional chemical synthesis methods or direct

sourcing from ergot fungi can be dangerous, inefficient, environmentally burdensome, and

difficult to standardize. By contrast, CB Therapeutics utilizes yeast-based precision fermentation

to produce bioidentical ergoline compounds with minimal waste, reduced carbon footprint, and

dependable yields at any scale.

 

   “Our goal is to unlock nature’s most promising compounds in the most

sustainable way,” said Sher Butt, MBA, Chief Executive Officer of CB Therapeutics. “By

adding ergolines to our synthetic biology platform, we’re helping to accelerate research and

commercialization pathways for partners who want to explore or develop new therapies in

neurology, mental health, and beyond.”

 

   “Our precision fermentation platform can deliver consistent, pure compounds for

use in translational research and product development. Our aim is to make these molecules

more accessible and sustainable, ultimately broadening their potential impact.” noted Jacob

Vogan, PhD, Chief Scientific Officer at CB Therapeutics

 

Key Advantages of CB Therapeutics’ Biosynthesis Platform:

  •       Sustainable Production: Precision fermentation significantly reduces toxic

byproducts and resource consumption compared to traditional extraction or chemical synthesis

methods.

  •       Scalability & Consistency: From small research batches to large-scale

manufacturing, the company’s bioreactors and integrated processing systems ensure high

quality precision fermentation batches.


  •       Broad Application Potential: Beyond psychedelic research (e.g., LSD

derivatives), ergoline-related compounds show promise in treating migraines, supporting

obstetric care, and exploring therapeutic avenues in neurology and psychiatry.

  •       Partnership Opportunities: CB Therapeutics actively seeks collaborations to

accelerate product development in pharmaceuticals, clinical research, and other emerging

markets worldwide.

 

For more information on partnership, licensing, or collaboration inquiries, please contact

Sher@cbthera.com

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